Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085352 | 0.95 | PTGS2 (0.58) | MMP3ESR1MEN1KMT2AADRA2A | |
| SCHEMBL28107125 | 0.93 | PTGS2 (0.61) | MMP3ESR1MEN1KMT2AADRA2A | |
| SCHEMBL8558569 | 0.89 | MMP3 (0.57) | MMP3ESR1MEN1KMT2AHSD17B1 | |
| SCHEMBL199210 | 0.87 | LPL (0.52) | LPLLIPGNPC1HPGDMAPK1 | |
| SCHEMBL27504332 | 0.86 | ESR1 (0.63) | ESR1MEN1KMT2AADRA2AADORA3 | |
| SCHEMBL11515483 | 0.85 | PSMB5 (0.49) | LPLLIPG | |
| SCHEMBL30500519 | 0.85 | PSMB5 (0.49) | LPLLIPG | |
| SCHEMBL29072264 | 0.84 | PTGS2 (0.55) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10599359 | 0.84 | PSMB5 (0.48) | MMP3LPLLIPG | |
| SCHEMBL27453997 | 0.83 | AOC3 (0.47) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |