Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15170453 | 0.83 | P2RX3 (0.42) | MEN1KMT2ALMNAP2RX3HDAC8 | |
| SCHEMBL16275009 | 0.82 | SMN1; SMN2 (0.49) | POLBLMNASMN1; SMN2TSHRNPC1 | |
| SCHEMBL15170666 | 0.76 | ALDH1A1 (0.38) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL858572 | 0.75 | MEN1 (0.48) | MEN1KMT2ALMNASMN1; SMN2TSHR | |
| SCHEMBL2032093 | 0.74 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2HCAR2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL17713984 | 0.72 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2HCAR2TSHRALDH1A1 | |
| SCHEMBL28297870 | 0.72 | PTPN1 (0.41) | P2RX3TSHR | |
| SCHEMBL1748938 | 0.71 | ALDH1A1 (0.59) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| Formaldehyde SCHEMBL27853879 | 0.70 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2HCAR2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL10559128 | 0.70 | KMO (0.43) | MEN1KMT2ALMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013115265-A1 | HETEROCYCLIC COMPOUND HAVING ANTI-HIV ACTIVITY | 富山化学工業株式会社 (JP) | 2013-08-08 | — | — | WO | disclosed |