Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670749 | 0.89 | TSHR (0.61) | TSHRKIF11MAPK1CYP1A2 | |
| SCHEMBL4472039 | 0.89 | TSHR (0.57) | TSHRMAPK1HIF1ACYP19A1MEN1 | |
| SCHEMBL151981 | 0.86 | TSHR (0.65) | TSHRMAPK1CYP1A2 | |
| SCHEMBL3903209 | 0.84 | TSHR (0.50) | TSHRKIF11MAPK1HIF1ACYP1A2 | |
| SCHEMBL11652133 | 0.84 | CYP19A1 (0.61) | TSHRKIF11MAPK1HIF1ACYP1A2 | |
| SCHEMBL1224870 | 0.84 | CYP19A1 (0.61) | TSHRKIF11MAPK1HIF1ACYP1A2 | |
| SCHEMBL367665 | 0.84 | CYP19A1 (0.61) | TSHRKIF11MAPK1HIF1ACYP1A2 | |
| SCHEMBL9577502 | 0.84 | TSHR (0.74) | TSHRKIF11MAPK1HIF1ACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL31241190 | 0.83 | TSHR (0.61) | TSHRMAPK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL15864874 | 0.83 | TSHR (0.61) | TSHRMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049642-A1 | METHOD FOR PRODUCING DIARYLKETONES AND ACID HALIDES | TESSENDERLO CHEMIE N.V. (BE) | 2001-07-12 | — | — | WO | claimed |
| WO-2002042246-A1 | METHOD FOR THE PREPARATION OF DICHLORODIARYLMETHANES | TESSENDERLO CHEMIE N.V. (BE) | 2002-05-30 | — | — | WO | disclosed |
| WO-2001049642-A1 | METHOD FOR PRODUCING DIARYLKETONES AND ACID HALIDES | TESSENDERLO CHEMIE N.V. (BE) | 2001-07-12 | — | — | WO | disclosed |
| US-4044060-A | PHOSGENE, THIONYL, PHOSPHORUS, ALDEHYDE, KETONE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-23 | — | — | US | disclosed |
| US-3985766-A | ANTIMYCOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |