Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.81 |
| ▸ | MAPT | P10636 | 10/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.81 |
| ▸ | GAA | P10253 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | HTT | P42858 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | IDO1 | P14902 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | GOT1 | P17174 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11887783 | 0.86 | MAPT (0.72) | MEN1KMT2AMAPTALOX12GAA | |
| SCHEMBL12049633 | 0.85 | MEN1 (0.76) | MEN1KMT2AMAPTALOX12GAA | |
| SCHEMBL176108 | 0.84 | IDO1 (0.70) | MEN1KMT2AMAPTALOX12GAA | |
| SCHEMBL734585 | 0.84 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL13719678 | 0.84 | MEN1 (0.72) | MEN1KMT2AMAPTALOX12GAA | |
| SCHEMBL5625480 | 0.83 | IDO1 (0.69) | MEN1KMT2AMAPTALOX12GAA | |
| SCHEMBL173465 | 0.82 | MAPT (0.68) | MEN1KMT2AMAPTALOX12GAA | |
| SCHEMBL14700058 | 0.80 | IDO1 (0.68) | MEN1KMT2AMAPTALOX12GAA | |
| SCHEMBL6028397 | 0.80 | IDO1 (0.68) | MEN1KMT2AMAPTALOX12GAA | |
| Methyl Tryptaminedithiocarbamate SCHEMBL2791255 | 0.80 | IDO1 (1.00) | MEN1KMT2AMAPTALOX12GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289083-A1 | IDO Inhibitors | NEWLINK GENETICS CORPORATION | 2013-10-31 | — | — | US | disclosed |
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | disclosed |
| US-7576245-B2 | Fluorous tagging and scavenging reactants and methods of synthesis and use thereof | FLUOROUS TECHNOLOGIES INCORPORATED (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576245-B2 | Fluorous tagging and scavenging reactants and methods of synthesis and use thereof | FLUOROUS TECHNOLOGIES INCORPORATED (US) | 2009-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053941-A1 | IDO Inhibitors | IDO1, IDO2, INMT | MEN1 2052/4885KMT2A 597/4885MAPT 2968/4885 |
| US-20130289083-A1 | IDO Inhibitors | IDO1, IDO2, INMT | MEN1 2267/4885KMT2A 660/4885MAPT 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.