Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921973 | 0.86 | SMN1; SMN2 (0.53) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL5502413 | 0.80 | KDM4E (0.59) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL19178491 | 0.79 | PPARD (0.72) | NPC1MEN1KMT2ARAB9ACASP3 | |
| SCHEMBL15211619 | 0.77 | POLB (0.52) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL17431383 | 0.77 | NPC1 (0.49) | NPC1MEN1KMT2ARAB9ACASP3 | |
| SCHEMBL15211452 | 0.77 | KDM4E (0.41) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL15211705 | 0.76 | MAPT (0.38) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL437186 | 0.75 | KMT2A (0.51) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL27516742 | 0.74 | MAOB (0.58) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL15211526 | 0.74 | TERT (0.47) | NPC1MEN1KMT2ARAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |