Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.40 |
| ▸ | PPARA | Q07869 | 8/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211853 | 0.81 | MBOAT4 (0.43) | PPARDPPARAPPARGFFAR1ESR1 | |
| SCHEMBL15211206 | 0.78 | PPARD (0.39) | PPARDPPARAPPARGFFAR1ESR1 | |
| SCHEMBL15211431 | 0.77 | TP53 (0.35) | PPARDPPARAESR1 | |
| SCHEMBL15212692 | 0.75 | ESR1 (0.35) | PPARDPPARAPPARGFFAR1ESR1 | |
| SCHEMBL15211500 | 0.75 | ESR1 (0.39) | PPARDPPARAPPARGFFAR1ESR1 | |
| SCHEMBL15211694 | 0.75 | IKBKB (0.36) | PPARDPPARAPPARGS1PR1ESR1 | |
| SCHEMBL15211378 | 0.74 | CA2 (0.40) | ESR1 | |
| SCHEMBL15211268 | 0.73 | NR4A2 (0.46) | PPARGFFAR1S1PR1S1PR5 | |
| SCHEMBL15211766 | 0.73 | PPARD (0.59) | PPARDPPARAMRGPRX4PPARGFFAR1 | |
| SCHEMBL17431385 | 0.72 | PPARD (0.74) | PPARDPPARAPPARGRXRANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |