Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3006418 | 0.98 | BRD4 (0.37) | BRD4CYP1A2HIF1AALDH1A1PPM1B | |
| SCHEMBL3010029 | 0.78 | ALDH1A1 (0.40) | ALDH1A1PPM1BPTPN1PPP1CCKMT2A | |
| SCHEMBL5924227 | 0.77 | — | — | |
| SCHEMBL9876671 | 0.76 | — | — | |
| SCHEMBL368280 | 0.74 | — | — | |
| SCHEMBL2597463 | 0.73 | BRD4 (0.45) | BRD4CYP1A2HIF1AALDH1A1MMP2 | |
| SCHEMBL1298896 | 0.72 | ATM (0.31) | — | |
| SCHEMBL7564595 | 0.72 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL7963075 | 0.72 | — | — | |
| SCHEMBL7953369 | 0.69 | HSD17B10 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464636-B1 | PROCESS FOR THE SYNTHESIS OF 2,4-DIOXOTETRAHYDROFURAN-3-CARBOXYLATES | BAYER IP GMBH (DE) | 2015-07-08 | — | — | EP | disclosed |
| US-8318955-B2 | Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates | BAYER CROPSCIENCE AG (DE) | 2012-11-27 | — | — | US | disclosed |
| EP-2464636-A1 | METHOD FOR PRODUCING 2,4-DIOXOTETRAHYDROFURANE-3-CARBOXYLATES | Bayer CropScience AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-20110060147-A1 | Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates | BAYER CROPSCIENCE AG (DE) | 2011-03-10 | — | — | US | disclosed |
| WO-2011018180-A1 | METHOD FOR PRODUCING 2,4-DIOXOTETRAHYDROFURANE-3-CARBOXYLATES | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060147-A1 | Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates | HDHD5, HACL2, IDUA | BRD4 2280/4885CYP1A2 406/4885HIF1A 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.