Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521211 | 0.98 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10TLR4 | |
| SCHEMBL3003984 | 0.97 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10TLR4 | |
| SCHEMBL1521223 | 0.78 | BRD4 (0.38) | ALDH1A1KMT2APPM1BPTPN1PPP1CC | |
| SCHEMBL7953369 | 0.71 | HSD17B10 (0.46) | ALDH1A1KDM4EHSD17B10MAPTGAA | |
| SCHEMBL5924227 | 0.71 | — | — | |
| SCHEMBL11622190 | 0.71 | CYP1A2 (0.38) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL31110744 | 0.70 | TDP2 (0.39) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL10886851 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4ETLR4MAPTMEN1 | |
| SCHEMBL354474 | 0.70 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3196831 | 0.70 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550745-B2 | Method for preparing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG (DE) | 2017-01-24 | — | — | US | disclosed |
| US-20120323023-A1 | METHOD FOR PREPARING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2012-12-20 | — | — | US | disclosed |
| US-8273904-B2 | Method for preparing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG (DE) | 2012-09-25 | — | — | US | disclosed |
| CN-101801948-A | Preparation method of 4-aminobut-2-enol lactone | BAYER CROPSCIENCE AG | 2010-08-11 | — | — | CN | disclosed |
| US-20100190990-A1 | Method for Producing 4-Aminobut-2-Enolides | BAYER CROPSCIENCE AG (DE) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190990-A1 | Method for Producing 4-Aminobut-2-Enolides | TUBB4B, UGT2B7, TUBB4A | ALDH1A1 295/4885KDM4E 1613/4885HPGD 1584/4885 |
| US-20120323023-A1 | METHOD FOR PREPARING 4-AMINOBUT-2-ENOLIDES | UGT2B7, TUBB4B, CYP1B1 | ALDH1A1 323/4885KDM4E 1671/4885HPGD 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.