SCHEMBL15212248

SCHEMBL15212248

C=CCN(c1cnc2ccccc2c1)S(=O)(=O)c1cc(Br)ccc1OC

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALPL P05186 11/20 0.56
ALDH1A1 P00352 1/20 0.49
MAPK1 P28482 1/20 0.49
TSHR P16473 1/20 0.46
MAPT P10636 1/20 0.44
HIF1A Q16665 1/20 0.44
EPAS1 Q99814 1/20 0.44
GAA P10253 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15212467 0.89 ALPL (0.55) ALPLALDH1A1MAPTHIF1AEPAS1
SCHEMBL15211957 0.88 ALPL (0.60) ALPLALDH1A1MAPK1TSHRMAPT
SCHEMBL15212056 0.86 ALPL (0.58) ALPLALDH1A1MAPK1TSHRHIF1A
SCHEMBL15212011 0.85 ALPL (0.59) ALPLALDH1A1MAPK1TSHRHIF1A
SCHEMBL15211975 0.85 ALPL (0.57) ALPLALDH1A1MAPK1TSHRHIF1A
SCHEMBL15212241 0.85 ALPL (0.57) ALPLALDH1A1MAPK1TSHRHIF1A
SCHEMBL15212047 0.84 ALPL (0.56) ALPLALDH1A1MAPK1TSHRHIF1A
SCHEMBL15212118 0.84 ALPL (0.56) ALPLALDH1A1MAPK1TSHRHIF1A
SCHEMBL15211733 0.83 ALPL (0.55) ALPLALDH1A1MAPK1TSHRHIF1A
SCHEMBL21226610 0.83 ALPL (0.54) ALPLALDH1A1MAPK1TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132214-A1 CURABLE COMPOSITION AND CURED PRODUCT 株式会社カネカ 2023-07-13 WO disclosed
WO-2022071387-A1 POLARIZING FILM, OPTICAL FILM, AND IMAGE DISPLAY DEVICE 日東電工株式会社 2022-04-07 WO disclosed
US-11066509-B2 Conductive paste composition, device comprising electrode formed from same, and method for producing conductive paste composition KANEKA CORPORATION (JP) 2021-07-20 US disclosed
WO-2021141037-A1 METHOD FOR PRODUCING POLARIZING FILM 日東電工株式会社 2021-07-15 WO disclosed
US-20210132274-A1 CURABLE RESIN COMPOSITION FOR POLARIZING FILMS, POLARIZING FILM AND METHOD FOR PRODUCING SAME NITTO DENKO CORPORATION (JP) 2021-05-06 US disclosed
WO-2020196625-A1 METHOD FOR MANUFACTURING POLARIZING FILM 日東電工株式会社 2020-10-01 WO disclosed
WO-2020196618-A1 POLARIZING FILM MANUFACTURING METHOD 日東電工株式会社 2020-10-01 WO disclosed
US-20200095370-A1 CONDUCTIVE PASTE COMPOSITION, DEVICE COMPRISING ELECTRODE FORMED FROM SAME, AND METHOD FOR PRODUCING CONDUCTIVE PASTE COMPOSITION KANEKA CORPORATION (JP) 2020-03-26 US disclosed
US-20200056051-A1 CURABLE RESIN COMPOSITION FOR OPTICAL FILMS, OPTICAL FILM AND METHOD FOR PRODUCING SAME NITTO DENKO CORPORATION (JP) 2020-02-20 US disclosed
WO-2019187904-A1 ALKALI DEVELOPING-TYPE PHOTOSENSITIVE RESIN COMPOSITION, DRY FILM, CURED PRODUCT AND PRINTED CIRCUIT BOARD 太陽インキ製造株式会社 2019-10-03 WO disclosed
US-9458147-B2 Sulfonamide compounds and uses as TNAP inhibitors SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2016-10-04 US disclosed
US-9458147-B2 Sulfonamide compounds and uses as TNAP inhibitors SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2016-10-04 US disclosed
US-9298096-B2 Curable resin composition, cured product thereof, printed circuit board comprising the same, and method for producing the cured product TAIYO INK MFG. CO., LTD. (JP) 2016-03-29 US disclosed
US-20150011551-A1 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS Sanford- Burnham Medical Reseach Institute (US) 2015-01-08 US disclosed
US-20150011551-A1 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS Sanford- Burnham Medical Reseach Institute (US) 2015-01-08 US disclosed
US-20150010735-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT THEREOF, PRINTED CIRCUIT BOARD COMPRISING THE SAME, AND METHOD FOR PRODUCING THE CURED PRODUCT TAIYO INK MFG. CO., LTD. (JP) 2015-01-08 US disclosed
US-20150011551-A1 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS Sanford- Burnham Medical Reseach Institute (US) 2015-01-08 US disclosed
EP-2817292-A1 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS Sanford-Burnham Medical Research Institute (US) 2014-12-31 EP disclosed
WO-2013126608-A1 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2013-08-29 WO disclosed
WO-2013126608-A1 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2013-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011551-A1 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS TNNI3, TNKS1BP1, TNNT2 ALPL 503/4885ALDH1A1 3674/4885MAPK1 3361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.