SCHEMBL15212822

SCHEMBL15212822

CCCCC(=O)CN1C(=O)C(NC(=O)OC(C)(C)C)CN(C2CCCCC2)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACE P12821 4/20 0.40
MME P08473 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SCN9A Q15858 5/20 0.38
CCKBR P32239 1/20 0.37
REN P00797 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6178297 0.87 CCKBR (0.43) ACEKMT2AL3MBTL1SCN9ACCKBR
SCHEMBL6181583 0.87 CCKBR (0.43) ACEKMT2AL3MBTL1SCN9ACCKBR
SCHEMBL6181104 0.87 CCKBR (0.43) ACEKMT2AL3MBTL1SCN9ACCKBR
SCHEMBL6178675 0.86 ACE (0.42) ACEKMT2AL3MBTL1SCN9ACCKBR
SCHEMBL6182762 0.86 SCN9A (0.43) ACEKMT2AL3MBTL1SCN9ACCKBR
SCHEMBL6177390 0.85 CCKBR (0.45) ACEKMT2AL3MBTL1SCN9ACCKBR
SCHEMBL7960849 0.84 CCKBR (0.47) ACEKMT2AL3MBTL1CCKBR
SCHEMBL6177387 0.83 ACE (0.40) ACEMMESCN9ACCKBR
SCHEMBL6178646 0.82 POLB (0.43) ACEKMT2AL3MBTL1SCN9ACCKBR
SCHEMBL7958947 0.81 SCN9A (0.40) ACEKMT2AL3MBTL1SCN9ACCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013126797-A1 CHOLECYSTOKININ B RECEPTOR TARGETING FOR IMAGING AND THERAPY PURDUE RESEARCH FOUNDATION (US) 2013-08-29 WO disclosed