Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15212923 | 0.81 | MAPT (0.44) | CA2MAPTSMN1; SMN2ALOX15HPGD | |
| SCHEMBL15211231 | 0.73 | SMN1; SMN2 (0.57) | CA2MAPTSMN1; SMN2ALOX15KDM4E | |
| SCHEMBL12474263 | 0.69 | LCK (0.44) | CA2MAPTSMN1; SMN2ALOX15HPGD | |
| SCHEMBL6136983 | 0.66 | AKR1B1 (0.52) | CA2MAPTHPGDHSD17B10LMNA | |
| SCHEMBL29051963 | 0.66 | AKR1B1 (0.61) | CA2MAPTHPGDHSD17B10LMNA | |
| SCHEMBL1650809 | 0.66 | KDM4E (0.50) | HPGDHSD17B10LMNAKDM4EGAA | |
| SCHEMBL2368215 | 0.65 | CYP3A4 (0.55) | HSD17B10TSHRALDH1A1MAPK1ESR1 | |
| SCHEMBL31266634 | 0.64 | AKR1B1 (0.43) | CA2MAPTSMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL23191190 | 0.63 | CYP3A4 (0.52) | HSD17B10TSHRMAPK1ESR1ESR2 | |
| SCHEMBL9623621 | 0.62 | CA1 (0.48) | CA2MAPTSMN1; SMN2ALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |