SCHEMBL6136983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4900831	0.83	CXCL8 (0.50)	AKR1B1CA2CAMK2ATTRCXCL8
	SCHEMBL11078314	0.82	AKR1B1 (0.67)	AKR1B1CA2CAMK2ATTRPOLB
	Hydrochloric Acid SCHEMBL11408340	0.81	CXCL8 (0.49)	AKR1B1CA2CAMK2ATTRCXCL8
	SCHEMBL21617921	0.78	AKR1B1 (0.45)	AKR1B1CA2CAMK2ATTRMAPT
	SCHEMBL6137046	0.78	CXCL8 (0.42)	AKR1B1CAMK2ATTRTDP1CXCL8
	SCHEMBL9477716	0.78	AKR1B1 (0.45)	AKR1B1CA2CAMK2ATTRCXCL8
	SCHEMBL30940438	0.76	AKR1B1 (0.58)	AKR1B1CA2CAMK2APOLBKDM4E
	SCHEMBL22798814	0.76	AKR1B1 (0.58)	AKR1B1CAMK2ATTRKDM4EMAPT
	SCHEMBL8685874	0.76	AKR1B1 (0.58)	AKR1B1CA2CAMK2APOLBKDM4E
	SCHEMBL29051963	0.75	AKR1B1 (0.61)	AKR1B1CA2CYP3A4MAPK1CAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.