Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650809 | 0.77 | KDM4E (0.50) | AKR1B1ALDH1A1LMNAGLAHPGD | |
| SCHEMBL205825 | 0.70 | ALOX15 (0.69) | LCKFYNAKR1B1GRB2SMN1; SMN2 | |
| SCHEMBL24950261 | 0.70 | KDM4E (0.68) | LCKFYNAKR1B1GRB2ALDH1A1 | |
| SCHEMBL15212927 | 0.69 | CA2 (0.40) | AKR1B1THRATHRBCAMK2ACA2 | |
| SCHEMBL15212923 | 0.69 | MAPT (0.44) | AKR1B1THRATHRBCA2ALDH1A1 | |
| SCHEMBL21585560 | 0.68 | TDP1 (0.66) | LCKFYNAKR1B1GRB2THRA | |
| SCHEMBL24938760 | 0.67 | ALOX15 (0.59) | LCKFYNAKR1B1GRB2THRA | |
| SCHEMBL156238 | 0.66 | TYR (0.60) | AKR1B1CAMK2ACA2ALDH1A1LMNA | |
| SCHEMBL29419312 | 0.66 | TYR (0.60) | AKR1B1CAMK2ACA2ALDH1A1LMNA | |
| SCHEMBL9121263 | 0.66 | MAOA (0.49) | AKR1B1CA2ALDH1A1CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675774-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE DIHYDROBENZOFURAN DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012111849-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE DIHYDROBENZOFURAN DERIVATIVE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-23 | — | — | WO | disclosed |