SCHEMBL15213287

SCHEMBL15213287

COC1OC(CO)C(O)C(OC2OC(CO)C(O)C(O)C2OC2OC(C)C(O)C(O)C2O)C1NC(C)=O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ LGALS3 P17931 5/20 0.51
▸ LGALS8 O00214 1/20 0.51
▸ LGALS4 P56470 1/20 0.51
▸ LGALS1 P09382 1/20 0.47
▸ LGALS7; LGALS7B P47929 1/20 0.47
▸ STAT3 P40763 4/20 0.47
▸ CD69 Q07108 1/20 0.46
▸ LGALS9 O00182 1/20 0.46
▸ AMY1A P0DUB6 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ THRB P10828 1/20 0.45
▸ MAPK1 P28482 2/20 0.44
▸ SELE P16581 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15258381 0.96 LGALS3 (0.48) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B
SCHEMBL25787341 0.96 LGALS3 (0.52) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B
SCHEMBL16407356 0.96 LGALS3 (0.52) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B
SCHEMBL21678048 0.96 LGALS3 (0.52) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B
SCHEMBL24495336 0.96 LGALS3 (0.52) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B
SCHEMBL23057244 0.96 LGALS3 (0.52) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B
SCHEMBL19453261 0.94 LGALS3 (0.48) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B
SCHEMBL25787418 0.94 LGALS3 (0.59) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B
SCHEMBL25787342 0.94 LGALS3 (0.59) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B
SCHEMBL18645639 0.93 LGALS3 (0.52) LGALS3LGALS8LGALS4LGALS1LGALS7; LGALS7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569230-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER Akeso Biomedical, Inc. (US) 2019-11-20 — — EP disclosed
US-20190314323-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER Akeso Biomedical, Inc. 2019-10-17 — — US disclosed
US-20190083447-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER Akeso Biomedical, Inc. 2019-03-21 — — US disclosed
US-10195172-B2 Reduction of gastrointestinal tract colonisation by Campylobacter Akeso Biomedical, Inc. (US) 2019-02-05 — — US disclosed
US-20170231945-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER Akeso Biomedical, Inc. 2017-08-17 — — US disclosed
US-20170231945-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER Akeso Biomedical, Inc. 2017-08-17 — — US disclosed
US-9655912-B2 Reduction of gastrointestinal tract colonisation by campylobacter Akeso Biomedical, Inc. (US) 2017-05-23 — — US disclosed
US-9655912-B2 Reduction of gastrointestinal tract colonisation by campylobacter Akeso Biomedical, Inc. (US) 2017-05-23 — — US disclosed
US-20150025026-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER MAHDAVI, JAFAR (GB) 2015-01-22 — — US disclosed
WO-2013121214-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER THE UNIVERSITY OF NOTTINGHAM (GB) 2013-08-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10195172-B2 Reduction of gastrointestinal tract colonisation by Campylobacter FABP2, MLN, SLC10A2 LGALS3 522/4885LGALS8 971/4885LGALS4 502/4885
US-20150025026-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER FABP2, MLN, MLNR LGALS3 673/4885LGALS8 1133/4885LGALS4 532/4885
US-20190083447-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER FABP2, MLN, MLNR LGALS3 673/4885LGALS8 1133/4885LGALS4 532/4885
US-20190314323-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER FABP2, MLN, MLNR LGALS3 623/4885LGALS8 1027/4885LGALS4 574/4885
US-20170231945-A1 REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER FABP2, MLN, MLNR LGALS3 673/4885LGALS8 1133/4885LGALS4 532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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