SCHEMBL15213816

SCHEMBL15213816

c1ccc(-c2ccc(-n3ccc4c5[nH]c6ccccc6c5ccc43)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.45
TDO2 P48775 5/20 0.42
HTR2B P41595 2/20 0.42
HTR5A P47898 2/20 0.42
NQO2 P16083 1/20 0.41
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41
GABRA1 P14867 2/20 0.41
GABRB1 P18505 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41
GABRA2 P47869 2/20 0.41
GABRB2 P47870 2/20 0.41
GABRA4 P48169 2/20 0.41
GABRE P78334 2/20 0.41
GABRA6 Q16445 2/20 0.41
GABRG1 Q8N1C3 2/20 0.41
GABRG3 Q99928 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15213818 0.93 KIF11 (0.49) KIF11TDO2HTR2BHTR5ANQO2
SCHEMBL30636672 0.93 KIF11 (0.49) KIF11TDO2HTR2BHTR5ANQO2
SCHEMBL15632037 0.89 KIF11 (0.43) KIF11TDO2HTR2BHTR5ANQO2
SCHEMBL15801515 0.88 KIF11 (0.47) KIF11TDO2HTR2BHTR5ANQO2
SCHEMBL15481693 0.88 KIF11 (0.42) KIF11TDO2HTR2BHTR5ANQO2
SCHEMBL15618123 0.86 FEN1 (0.38) KIF11GABRA1GABRG2GABRB3GABRA5
SCHEMBL15596488 0.84 AR (0.43) TDO2GABRPGABRDGABRA1GABRB1
SCHEMBL15632057 0.81 NQO2 (0.40) KIF11TDO2HTR2BHTR5ANQO2
SCHEMBL15618128 0.81 KDM4E (0.41) KIF11NQO2GABRPGABRDGABRA1
SCHEMBL15596507 0.81 KIF11 (0.44) KIF11TDO2HTR2BHTR5ANQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 US disclosed
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 US disclosed
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
WO-2014065498-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 (KR) 2014-05-01 WO disclosed
WO-2014046392-A1 ORGANIC COMPOUND AND ELECTROLUMINESCENT ELEMENT HAVING SAME 주식회사 두산 (KR) 2014-03-27 WO disclosed
WO-2014027822-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-02-20 WO disclosed
WO-2013122364-A2 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE THEREWITH 덕산하이메탈(주) (KR) 2013-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same IDO1, IDO2, KYNU KIF11 1738/4885TDO2 29/4885HTR2B 291/4885
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME INMT, IDO1, IDO2 KIF11 642/4885TDO2 52/4885HTR2B 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.