Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470686 | 0.83 | MEN1 (0.63) | MEN1KMT2ARAB9AHPGDNPC1 | |
| SCHEMBL15214218 | 0.78 | KMT2A (0.52) | MEN1KMT2AHPGDSMN1; SMN2POLB | |
| SCHEMBL21851372 | 0.72 | MAPT (0.48) | MEN1KMT2ARAB9AHPGDNPC1 | |
| Oxalic Acid SCHEMBL2333397 | 0.72 | KMT2A (0.59) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3512632 | 0.71 | TYK2 (0.73) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13485752 | 0.71 | HPGD (0.59) | MEN1KMT2ARAB9AHPGDNPC1 | |
| SCHEMBL7706279 | 0.71 | HPGD (0.59) | MEN1KMT2ARAB9AHPGDNPC1 | |
| SCHEMBL15296547 | 0.70 | HPGD (0.55) | MEN1KMT2ARAB9AHPGDNPC1 | |
| SCHEMBL3470521 | 0.68 | ALDH1A1 (0.52) | MEN1KMT2ARAB9AHPGDNPC1 | |
| SCHEMBL12121109 | 0.67 | HPGD (0.68) | MEN1KMT2ARAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518940-B2 | FP-pocket-binding effectors and methods for using the same to modulate telomerase activity | THE WISTAR INSTITUTE (US) | 2013-08-27 | — | — | US | disclosed |