Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470125 | 0.83 | KMT2A (0.63) | KMT2AMAPTMEN1HPGDPOLB | |
| SCHEMBL15214217 | 0.78 | MEN1 (0.47) | KMT2AMAPTMEN1HPGDPOLB | |
| SCHEMBL3819641 | 0.70 | HPGD (0.60) | KMT2AMAPTMEN1HPGDPOLB | |
| SCHEMBL9778626 | 0.70 | ALDH1A1 (0.68) | KMT2AMAPTMEN1HPGDPOLB | |
| SCHEMBL6598806 | 0.67 | TSHR (0.53) | KMT2AMAPTMEN1LMNATSHR | |
| SCHEMBL28051805 | 0.67 | P2RX7 (0.54) | TSHR | |
| SCHEMBL11777386 | 0.67 | MAPT (0.46) | KMT2AMAPTMEN1CYP1A2ALDH1A1 | |
| SCHEMBL9556295 | 0.67 | POLB (0.52) | KMT2AMAPTMEN1HPGDPOLB | |
| SCHEMBL7223858 | 0.66 | HPGD (0.68) | KMT2AMAPTMEN1HPGDPOLB | |
| SCHEMBL29092068 | 0.66 | HPGD (0.66) | KMT2AMAPTMEN1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518940-B2 | FP-pocket-binding effectors and methods for using the same to modulate telomerase activity | THE WISTAR INSTITUTE (US) | 2013-08-27 | — | — | US | disclosed |