SCHEMBL15214249

SCHEMBL15214249

CCOC(Cn1cc(C)nn1)(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18377933 0.73 DPP4 (0.38) DPP4
SCHEMBL19006343 0.72 ALDH1A1 (0.38) ALDH1A1LMNA
SCHEMBL764212 0.72
SCHEMBL25757821 0.72 FFAR1 (0.38) DPP4
SCHEMBL16377851 0.72 DPP4 (0.34) DPP4ALDH1A1LMNA
SCHEMBL25974212 0.70 DPP4 (0.33) DPP4
SCHEMBL10065962 0.69 DPP4 (0.39) DPP4
SCHEMBL2628202 0.69
SCHEMBL21166171 0.68 DPP4 (0.38) DPP4
SCHEMBL15214248 0.68 KDM4E (0.38) DPP4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9132188-B2 Chemically Programmed Vaccination THE SCRIPPS RESEARCH INSTITUTE (US) 2015-09-15 US disclosed
US-8518927-B2 Chemically programmed vaccination THE SCRIPPS RESEARCH INSTITUTE (US) 2013-08-27 US disclosed