Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3192497 | 0.78 | KDM4E (0.30) | KMT2ARXFP1 | |
| SCHEMBL15246613 | 0.77 | PDE4A (0.32) | — | |
| SCHEMBL1008469 | 0.64 | ADORA2A (0.31) | ADORA2A | |
| SCHEMBL4058851 | 0.64 | KMT2A (0.33) | KMT2AADORA2A | |
| Iodide SCHEMBL1609671 | 0.62 | KMT2A (0.32) | KMT2AADORA2A | |
| SCHEMBL141994 | 0.58 | GSK3A (0.44) | ADORA2A | |
| SCHEMBL21891275 | 0.53 | ALDH1A1 (0.33) | KMT2AADORA2A | |
| SCHEMBL7083772 | 0.53 | GSK3A (0.39) | ADORA2A | |
| SCHEMBL13325450 | 0.53 | ADORA2A (0.41) | KMT2ARXFP1ADORA2A | |
| SCHEMBL13024384 | 0.53 | ADORA2A (0.41) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660444-B1 | METAL COMPLEXES OF N-HETEROCYCLIC CARBENES AS RADIOPHARMACEUTICALS AND ANTIBIOTICS | UNIV AKRON (US) | 2014-11-12 | — | — | EP | disclosed |
| US-8519146-B2 | Purine or imidazole and silver complexes; therapeutic, antimicrobial, and antifungal compounds; urinary tract infections | THE UNIVERSITY OF AKRON (US) | 2013-08-27 | — | — | US | disclosed |