Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058851 | 0.65 | KMT2A (0.33) | ADORA2A | |
| Iodide SCHEMBL1609671 | 0.64 | KMT2A (0.32) | ADORA2A | |
| SCHEMBL15214970 | 0.64 | KMT2A (0.31) | ADORA2A | |
| SCHEMBL3192497 | 0.63 | KDM4E (0.30) | — | |
| SCHEMBL141994 | 0.59 | GSK3A (0.44) | ADORA2A | |
| SCHEMBL7532405 | 0.55 | ALDH1A1 (0.40) | ADORA2A | |
| SCHEMBL10724834 | 0.55 | POLB (0.36) | ADORA2A | |
| SCHEMBL21891275 | 0.54 | ALDH1A1 (0.33) | ADORA2A | |
| SCHEMBL7083772 | 0.54 | GSK3A (0.39) | ADORA2A | |
| SCHEMBL13024384 | 0.54 | ADORA2A (0.41) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268652-B1 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2012-12-19 | — | — | EP | disclosed |
| EP-2268652-A2 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009118475-A2 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-10-01 | — | — | WO | disclosed |