Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15214970 | 0.78 | KMT2A (0.31) | KMT2ARXFP1 | |
| SCHEMBL4058851 | 0.63 | KMT2A (0.33) | KDM4EKMT2A | |
| SCHEMBL1008469 | 0.63 | ADORA2A (0.31) | — | |
| SCHEMBL21203108 | 0.62 | — | — | |
| Iodide SCHEMBL1609671 | 0.61 | KMT2A (0.32) | KDM4EKMT2A | |
| SCHEMBL15246613 | 0.61 | PDE4A (0.32) | — | |
| SCHEMBL19423846 | 0.58 | ADRA2C (0.43) | KMT2A | |
| SCHEMBL141994 | 0.57 | GSK3A (0.44) | — | |
| SCHEMBL19981061 | 0.54 | — | — | |
| SCHEMBL10216413 | 0.54 | MAPT (0.44) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065335-A1 | Polynucleotide intercalator interceptors and inhibitors | MATERIALS EVOLUTION AND DEVELOPMENT USA, INC | 2005-03-24 | — | — | US | claimed |
| EP-1318796-A2 | POLYNUCLEOTIDE INTERCALATOR INTERCEPTORS AND INHIBITORS | Lyles, Mark B. (US) | 2003-06-18 | — | — | EP | claimed |
| WO-2002045707-A2 | POLYNUCLEOTIDE INTERCALATOR INTERCEPTORS AND INHIBITORS | LYLES MARK B (US) | 2002-06-13 | — | — | WO | claimed |
| US-7662767-B2 | Polynucleotide intercalator interceptors and inhibitors | MATERIALS EVOLUTION AND DEVELOPMENT USA, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| US-20050065335-A1 | Polynucleotide intercalator interceptors and inhibitors | MATERIALS EVOLUTION AND DEVELOPMENT USA, INC | 2005-03-24 | — | — | US | disclosed |
| EP-1318796-A2 | POLYNUCLEOTIDE INTERCALATOR INTERCEPTORS AND INHIBITORS | Lyles, Mark B. (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002045707-A2 | POLYNUCLEOTIDE INTERCALATOR INTERCEPTORS AND INHIBITORS | LYLES MARK B (US) | 2002-06-13 | — | — | WO | disclosed |