Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 17/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15215124 | 0.89 | CSF1R (0.51) | CSF1RNNMT | |
| SCHEMBL15215111 | 0.87 | CSF1R (0.47) | CSF1RCYP3A4CYP2C9 | |
| SCHEMBL15215106 | 0.79 | CSF1R (0.48) | CSF1RNNMT | |
| SCHEMBL15215123 | 0.76 | TSHR (0.52) | CSF1R | |
| SCHEMBL15215128 | 0.74 | GRM2 (0.47) | LRRK2 | |
| SCHEMBL15215117 | 0.74 | CHEK1 (0.41) | CSF1RLRRK2 | |
| SCHEMBL5929762 | 0.74 | CSF1R (0.61) | CSF1R | |
| SCHEMBL15215122 | 0.73 | GRM2 (0.46) | CSF1RLRRK2 | |
| SCHEMBL5929749 | 0.72 | CSF1R (0.59) | CSF1R | |
| SCHEMBL15215125 | 0.71 | TSHR (0.44) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225524-A1 | Chemical Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225524-A1 | Chemical Compounds | LDHA, NQO2, LDHB | CSF1R 2683/4885LRRK2 1463/4885NNMT 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.