Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15215122 | 0.87 | GRM2 (0.46) | GRM2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL15215129 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EMEN1LRRK2 | |
| SCHEMBL15215104 | 0.74 | CSF1R (0.58) | LRRK2 | |
| SCHEMBL15215121 | 0.72 | MPO (0.40) | ALDH1A1KDM4ELRRK2 | |
| SCHEMBL31673858 | 0.69 | KDM1A (0.54) | KMT2AKDM4EMEN1LMNAMAPT | |
| SCHEMBL23629059 | 0.68 | CSF1R (0.53) | ALDH1A1KMT2AKDM4EMEN1LRRK2 | |
| SCHEMBL15215111 | 0.67 | CSF1R (0.47) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL31673741 | 0.67 | LIMK1 (0.46) | GRM2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL27642254 | 0.66 | GRM2 (0.65) | GRM2ALDH1A1 | |
| SCHEMBL27623216 | 0.66 | GRM2 (0.69) | GRM2LMNADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225524-A1 | Chemical Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225524-A1 | Chemical Compounds | LDHA, NQO2, LDHB | GRM2 3531/4885ALDH1A1 33/4885KMT2A 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.