Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15216492 | 0.79 | GAA (0.42) | ALDH1A1KMT2ATDP1TP53GAA | |
| SCHEMBL15216487 | 0.77 | FBP1 (0.50) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL28566965 | 0.77 | FBP1 (0.50) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL20973072 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KMT2ATDP1HDAC4MEF2D | |
| SCHEMBL21000183 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KMT2ATDP1HDAC4MEF2D | |
| SCHEMBL4711176 | 0.76 | FBP1 (0.49) | ALDH1A1KMT2ATDP1 | |
| SCHEMBL15216495 | 0.76 | FBP1 (0.49) | TDP1CYP1A2 | |
| SCHEMBL15216509 | 0.76 | FBP1 (0.49) | ALDH1A1KMT2ATDP1MAPTCYP1A2 | |
| SCHEMBL7922822 | 0.76 | FBP1 (0.49) | TDP1CYP1A2 | |
| SCHEMBL11408231 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KMT2ATP53KIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225694-A1 | COMPOSITIONS AND METHODS OF INHIBITING RETINAL DEGENERATION | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225694-A1 | COMPOSITIONS AND METHODS OF INHIBITING RETINAL DEGENERATION | ALDH1A2, PDE6C, NQO1 | ALDH1A1 283/4885KMT2A 4552/4885TDP1 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.