Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15216574 | 0.93 | SLC6A2 (0.62) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL10038669 | 0.91 | ALDH1A1 (0.60) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL1047553 | 0.87 | MAPT (0.70) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL257695 | 0.85 | L3MBTL1 (0.56) | MAPTL3MBTL1CYP3A4MAPK1POLB | |
| SCHEMBL4048052 | 0.82 | ALDH1A1 (0.51) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL545380 | 0.80 | — | — | |
| Pyrazine SCHEMBL27515795 | 0.80 | MAPT (0.65) | MAPTL3MBTL1POLBNPC1RAB9A | |
| SCHEMBL3695529 | 0.79 | ALDH1A1 (0.62) | MAPTL3MBTL1CYP1A2CYP3A4TSHR | |
| SCHEMBL1311400 | 0.79 | L3MBTL1 (0.54) | MAPTL3MBTL1MAPK1POLBNPC1 | |
| Ammonia Solution, Strong SCHEMBL27496972 | 0.78 | MAPT (0.63) | MAPTL3MBTL1MAPK1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10261021-B2 | Method and device for detecting alkylating agents | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2019-04-16 | — | — | US | disclosed |
| EP-2630481-B1 | A method and kit for detecting alkylating agents | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2017-09-13 | — | — | EP | disclosed |
| US-20130224876-A1 | A METHOD AND DEVICE FOR DETECTING ALKYLATING AGENTS | Univeristy College Cardiff Consultants Limited | 2013-08-29 | — | — | US | disclosed |
| US-20130224876-A1 | A METHOD AND DEVICE FOR DETECTING ALKYLATING AGENTS | Univeristy College Cardiff Consultants Limited | 2013-08-29 | — | — | US | disclosed |