Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337451 | 0.84 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL13132319 | 0.84 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL21210556 | 0.83 | GAA (0.42) | SIGMAR1GAAGBA1 | |
| SCHEMBL9801163 | 0.81 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL25944376 | 0.76 | — | — | |
| SCHEMBL17624338 | 0.76 | FNTA (0.31) | SIGMAR1 | |
| SCHEMBL18885236 | 0.76 | GAA (0.33) | GAAGBA1 | |
| SCHEMBL27281638 | 0.76 | GAA (0.33) | GAAGBA1 | |
| SCHEMBL29646200 | 0.76 | GAA (0.33) | GAAGBA1 | |
| SCHEMBL9801291 | 0.75 | ALOX15 (0.41) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016047-B1 | BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11- BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2013-08-28 | — | — | EP | disclosed |