Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19496237 | 0.92 | L3MBTL1 (0.39) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 | |
| SCHEMBL81624 | 0.92 | L3MBTL1 (0.39) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 | |
| SCHEMBL22519024 | 0.86 | L3MBTL1 (0.41) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 | |
| SCHEMBL18563138 | 0.84 | KDM4E (0.38) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 | |
| SCHEMBL3436969 | 0.83 | L3MBTL1 (0.46) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 | |
| SCHEMBL12772837 | 0.83 | L3MBTL3 (0.46) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 | |
| SCHEMBL736095 | 0.82 | KDM4E (0.47) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 | |
| SCHEMBL1646548 | 0.82 | KDM4E (0.47) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 | |
| SCHEMBL736305 | 0.82 | KDM4E (0.47) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 | |
| SCHEMBL82229 | 0.82 | KDM4E (0.50) | L3MBTL1L3MBTL3PIM1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225528-A1 | Phosphorus Derivatives as Kinase Inhibitors | ARIAD PHARMACEUTICALS, INC. (US) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225528-A1 | Phosphorus Derivatives as Kinase Inhibitors | PHKA1, PIK3CA, PHKA2 | L3MBTL1 4738/4885L3MBTL3 4709/4885PIM1 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.