SCHEMBL15217834

SCHEMBL15217834

O=C(Nc1ccccc1)N1CCN(Cc2cc3ccccc3cc2O)CC1

nearest known ligand 0.73

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 19/20 0.73
KDM4E B2RXH2 1/20 0.61
MAPT P10636 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3599605 0.84 FAAH (1.00) FAAHKDM4EMAPT
SCHEMBL3604735 0.84 FAAH (1.00) FAAHKDM4EMAPT
SCHEMBL3595624 0.83 FAAH (1.00) FAAHKDM4EMAPT
SCHEMBL3606740 0.81 FAAH (1.00) FAAHKDM4EMAPT
SCHEMBL3590361 0.81 FAAH (1.00) FAAHKDM4EMAPT
SCHEMBL3606503 0.81 FAAH (1.00) FAAHKDM4EMAPT
SCHEMBL3603324 0.80 FAAH (1.00) FAAHKDM4EMAPT
SCHEMBL3596348 0.78 FAAH (1.00) FAAHKDM4EMAPT
SCHEMBL3602097 0.78 FAAH (1.00) FAAHKDM4EMAPT
SCHEMBL16691067 0.78 FAAH (0.74) FAAHKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130224151-A1 Use of FAAH Inhibitors for Treating Abdominal, Visceral and Pelvic Pain UNITED STATES OF AMERICA (US) 2013-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130224151-A1 Use of FAAH Inhibitors for Treating Abdominal, Visceral and Pelvic Pain FAAH, FAAH2, PNLIP FAAH 1/4885KDM4E 2676/4885MAPT 4229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.