SCHEMBL152187

SCHEMBL152187

Clc1cc2[nH]c[c]c2cc1Br

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.44
AHR P35869 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4851597 0.83
SCHEMBL6011023 0.76 ALDH1A1 (0.42)
SCHEMBL10355483 0.72 TSHR (0.39)
SCHEMBL9741830 0.72
SCHEMBL9739128 0.68
SCHEMBL207535 0.67 AHR (0.42) CSNK2A1AHR
SCHEMBL207490 0.67 AHR (0.42) AHR
SCHEMBL4885600 0.67 CSNK2A1 (0.32) CSNK2A1
SCHEMBL1965665 0.66 GPR84 (0.37)
SCHEMBL9740880 0.66 SRC (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116411043-A Chromogenic medium for detecting vibrio vulnificus and vibrio cholerae and preparation method thereof 广东省科学院微生物研究所(广东省微生物分析检测中心) 2023-07-11 CN claimed
CN-116103362-A Chromogenic medium for detecting vibrio parahaemolyticus 广东省科学院微生物研究所(广东省微生物分析检测中心) 2023-05-12 CN claimed
CN-116064717-A Chromogenic medium for detecting various pathogenic vibrios 广东省科学院微生物研究所(广东省微生物分析检测中心) 2023-05-05 CN claimed
CN-106591416-B Chromogenic medium for detecting food-borne pathogenic yersinia 中国检验检疫科学研究院 2020-06-30 CN claimed
US-10241109-B2 Method of stabilizing molecules without refrigeration using water soluble polymers and applications thereof in performing chemical reactions MCMASTER UNIVERSITY (CA) 2019-03-26 US claimed
US-9932645-B2 Method for detecting bacteriolytic conditions in a sample UNIVERSITAT DE BARCELONA (ES) 2018-04-03 US claimed
EP-2181330-B2 COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS STATENS SERUMINSTITUT (DK) 2016-08-31 EP claimed
US-9157109-B2 Biosensors utilizing ink jet-printed biomolecule compatible sol gel inks and uses thereof MCMASTER UNIVERSITY (CA) 2015-10-13 US claimed
WO-2015066819-A1 METHOD OF STABILIZING MOLECULES WITHOUT REFRIGERATION USING WATER SOLUBLE POLYMERS AND APPLICATIONS THEREOF IN PERFORMING CHEMICAL REACTIONS FILIPE CARLOS (CA) 2015-05-14 WO claimed
US-8859256-B2 Method for detecting replication or colonization of a biological therapeutic GENELUX CORPORATION (US) 2014-10-14 US claimed
EP-2122350-A2 DETECTION OF ANALYTES Do-Coop Technologies Ltd (IL) 2009-11-25 EP claimed
WO-2008081455-A2 DETECTION OF ANALYTES DO-COOP TECHNOLOGIES LTD. (IL) 2008-07-10 WO claimed
US-7323488-B2 Chromogenic enzyme substrates BURTON MICHAEL 2008-01-29 US claimed
WO-2008009046-A1 DETECTION OF ENZYMES AND MICROORGANISMS AND DEVICES THEREFOR ENVIRONMENTAL BIOTECHNOLOGY CRC PTY LIMITED (AU) 2008-01-24 WO claimed
EP-1436411-B1 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2005-12-14 EP claimed
EP-1334205-B1 METHOD FOR IDENTIFYING LISTERIA MONOCYTOGENES AND CULTURE MEDIUM BIOMERIEUX SA (FR) 2005-10-26 EP claimed
US-20050124556-A1 Chromogenic enzyme substrates BURTON MICHAEL (GB) 2005-06-09 US claimed
EP-1436411-A2 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY Burton, Michael (GB) 2004-07-14 EP claimed
WO-2003035896-A2 CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY BURTON MICHAEL (GB) 2003-05-01 WO claimed
EP-0476930-B1 Enzyme assays SANKYO CO (JP) 1997-11-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124556-A1 Chromogenic enzyme substrates DCXR, MGAM, IDE CSNK2A1 2578/4885AHR 1326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.