Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | USP2 | O75604 | 5/20 | 0.56 |
| ▸ | CNR2 | P34972 | 6/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522506 | 0.90 | KDM4E (0.54) | KDM4EUSP2CNR2CNR1MEN1 | |
| SCHEMBL1522633 | 0.90 | CNR2 (0.54) | KDM4EUSP2CNR2CNR1MEN1 | |
| SCHEMBL1522418 | 0.90 | CNR2 (0.54) | KDM4EUSP2CNR2CNR1MEN1 | |
| SCHEMBL1522381 | 0.85 | CNR2 (0.62) | KDM4EUSP2CNR2CNR1MEN1 | |
| SCHEMBL1523115 | 0.85 | CNR2 (0.60) | KDM4EUSP2CNR2CNR1MEN1 | |
| SCHEMBL1522518 | 0.84 | CNR2 (0.55) | KDM4EUSP2CNR2CNR1MEN1 | |
| SCHEMBL1522995 | 0.82 | CNR2 (0.55) | KDM4EUSP2CNR2CNR1MEN1 | |
| SCHEMBL1522261 | 0.82 | CNR2 (0.55) | KDM4EUSP2CNR2CNR1MEN1 | |
| SCHEMBL1522556 | 0.81 | CNR2 (0.56) | KDM4EUSP2CNR2CNR1MEN1 | |
| SCHEMBL1522333 | 0.80 | CNR2 (0.53) | KDM4EUSP2CNR2CNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097492-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885USP2 3734/4885CNR2 4494/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885USP2 3734/4885CNR2 4494/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | KDM4E 4075/4885USP2 3368/4885CNR2 4140/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | KDM4E 3897/4885USP2 2866/4885CNR2 4150/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885USP2 3734/4885CNR2 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.