Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881616 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HTTFAAHLMNA | |
| SCHEMBL15205816 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1HTTFAAHNPSR1 | |
| SCHEMBL4757751 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1FAAHPRKAA2 | |
| SCHEMBL15205904 | 0.80 | GPR119 (0.43) | KDM4EALDH1A1HTTHPGDMAPT | |
| SCHEMBL210157 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1FAAHLMNAMEN1 | |
| SCHEMBL17108787 | 0.79 | SMN1; SMN2 (0.50) | KDM4EALDH1A1HTT | |
| SCHEMBL1880665 | 0.79 | SMN1; SMN2 (0.54) | KDM4EALDH1A1 | |
| SCHEMBL23501608 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1HTTMAPTPOLB | |
| SCHEMBL112800 | 0.78 | MC4R (0.47) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29934142 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1HTTMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |
| EP-2634176-A1 | PYRIDINE DERIVATIVE AND MEDICINAL AGENT | Nippon Shinyaku Co., Ltd. (JP) | 2013-09-04 | — | — | EP | disclosed |