Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 6/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | TCF4 | P15884 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660350 | 0.82 | BACE1 (0.53) | MAOAMAOBAPPESR1ESR2 | |
| SCHEMBL5958944 | 0.81 | APP (0.55) | MAOAMAOBAPPTERTPSMB5 | |
| SCHEMBL483701 | 0.80 | NCF1 (0.54) | MAOAMAOBAPPMAPTMEN1 | |
| SCHEMBL12324757 | 0.78 | NPC1 (0.60) | MAPTBACE1MEN1KMT2AKDM4E | |
| SCHEMBL20660342 | 0.78 | BACE1 (0.55) | ESR1ESR2MAPTBACE1 | |
| SCHEMBL5960160 | 0.77 | MAPT (0.47) | APPMAPT | |
| SCHEMBL483940 | 0.76 | SNCA (0.55) | MAOAMAOBAPPTERTPSMB5 | |
| SCHEMBL23926483 | 0.75 | ALDH1A1 (0.45) | APPMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL30123613 | 0.75 | ALDH1A1 (0.45) | APPMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7744331 | 0.75 | ALDH1A1 (0.50) | APAF1APPTERTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103380118-A | Tau imaging probe | CLINO LTD | 2013-10-30 | — | — | CN | claimed |
| EP-2634177-A1 | TAU IMAGING PROBE | Clino Ltd. (JP) | 2013-09-04 | — | — | EP | claimed |
| US-9701637-B2 | Tau imaging probe | GE HEALTHCARE LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-9701637-B2 | Tau imaging probe | GE HEALTHCARE LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-9701637-B2 | Tau imaging probe | GE HEALTHCARE LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-9452985-B2 | Tau imaging probe | GE HEALTHCARE LIMITED (GB) | 2016-09-27 | — | — | US | disclosed |
| US-9452985-B2 | Tau imaging probe | GE HEALTHCARE LIMITED (GB) | 2016-09-27 | — | — | US | disclosed |
| US-9452985-B2 | Tau imaging probe | GE HEALTHCARE LIMITED (GB) | 2016-09-27 | — | — | US | disclosed |
| US-20160271278-A1 | TAU IMAGING PROBE | GE HEALTHCARE LTD (GB) | 2016-09-22 | — | — | US | disclosed |
| US-20160271278-A1 | TAU IMAGING PROBE | GE HEALTHCARE LTD (GB) | 2016-09-22 | — | — | US | disclosed |
| US-20160271278-A1 | TAU IMAGING PROBE | GE HEALTHCARE LTD (GB) | 2016-09-22 | — | — | US | disclosed |
| US-9249101-B2 | Tau imaging probe | CLINO LTD. (JP) | 2016-02-02 | — | — | US | disclosed |
| US-9249101-B2 | Tau imaging probe | CLINO LTD. (JP) | 2016-02-02 | — | — | US | disclosed |
| US-9249101-B2 | Tau imaging probe | CLINO LTD. (JP) | 2016-02-02 | — | — | US | disclosed |
| US-20160008494-A1 | TAU IMAGING PROBE | GE HEALTHCARE LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160008494-A1 | TAU IMAGING PROBE | GE HEALTHCARE LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160008494-A1 | TAU IMAGING PROBE | GE HEALTHCARE LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20130324523-A1 | TAU IMAGING PROBE | CLINO LTD. (JP) | 2013-12-05 | — | — | US | disclosed |
| CN-103380118-A | Tau imaging probe | CLINO LTD | 2013-10-30 | — | — | CN | disclosed |
| EP-2634177-A1 | TAU IMAGING PROBE | Clino Ltd. (JP) | 2013-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008494-A1 | TAU IMAGING PROBE | MAPT, APP, APBA1 | MAOA 3768/4885MAOB 2859/4885APAF1 2855/4885 |
| US-20130324523-A1 | TAU IMAGING PROBE | MAPT, APP, APBA1 | MAOA 3768/4885MAOB 2859/4885APAF1 2855/4885 |
| US-20160271278-A1 | TAU IMAGING PROBE | MAPT, APP, APBA1 | MAOA 3768/4885MAOB 2859/4885APAF1 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.