Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522311 | 0.86 | PTGDR2 (0.43) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL1522224 | 0.86 | MAPT (0.46) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL1522441 | 0.84 | TP53 (0.45) | KDM4EALDH1A1PTGDR2CYP1A2CYP2D6 | |
| SCHEMBL1523150 | 0.84 | PTGDR2 (0.53) | KDM4EALDH1A1PTGDR2PKMMEN1 | |
| SCHEMBL1523366 | 0.81 | PTGDR2 (0.51) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL1522698 | 0.80 | PTGDR2 (0.51) | KDM4EALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL1522225 | 0.77 | PTGDR2 (0.55) | KDM4EALDH1A1PTGDR2MAPTTP53 | |
| SCHEMBL1522600 | 0.76 | MAPT (0.43) | KDM4EALDH1A1PTGDR2MAPTTP53 | |
| SCHEMBL1522234 | 0.76 | MCL1 (0.44) | KDM4EALDH1A1MAPTTP53THRB | |
| SCHEMBL1523043 | 0.76 | MAPT (0.46) | KDM4EALDH1A1PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097492-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885ALDH1A1 1434/4885PTGDR2 4141/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885ALDH1A1 1434/4885PTGDR2 4141/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | KDM4E 4075/4885ALDH1A1 891/4885PTGDR2 4076/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | KDM4E 3897/4885ALDH1A1 1592/4885PTGDR2 4088/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885ALDH1A1 1434/4885PTGDR2 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.