Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522408 | 0.87 | MAPT (0.43) | PTGDR2MAPTCYP19A1ELANETHRB | |
| SCHEMBL1522698 | 0.84 | PTGDR2 (0.51) | PTGDR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL1522225 | 0.84 | PTGDR2 (0.55) | PTGDR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL1522441 | 0.84 | TP53 (0.45) | PTGDR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL1523366 | 0.83 | PTGDR2 (0.51) | PTGDR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL1522645 | 0.82 | PTGDR2 (0.44) | PTGDR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL1523317 | 0.81 | MAPT (0.59) | PTGDR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL3513813 | 0.81 | PTGDR2 (0.55) | PTGDR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL1522968 | 0.81 | PTGDR2 (0.45) | PTGDR2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL1715052 | 0.80 | IDO1 (0.48) | TP53MAPTCYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| CN-1735612-A | Anti-infective agents | ABBOTT LAB (US) | 2006-02-15 | — | — | CN | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | PTGDR2 4141/4885TP53 3666/4885MAPT 4106/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | PTGDR2 4076/4885TP53 3890/4885MAPT 4529/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | PTGDR2 4088/4885TP53 3573/4885MAPT 4234/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | PTGDR2 4141/4885TP53 3666/4885MAPT 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.