SCHEMBL15225100

SCHEMBL15225100

CC(SSc1ccccn1)(C(=O)ON1C(=O)CCC1=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.35
EHMT1 Q9H9B1 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
GAA P10253 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 5/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 5/20 0.32
TDP1 Q9NUW8 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 2/20 0.32
HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22414810 0.79 LMNA (0.38) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL29414992 0.79 LMNA (0.38) EHMT2EHMT1APOBEC3GALDH1A1LMNA
Hydrochloric Acid SCHEMBL30767154 0.78 LMNA (0.38) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL30952819 0.78 LMNA (0.38) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL13658486 0.78 LMNA (0.38) EHMT2EHMT1APOBEC3GALDH1A1LMNA
Hydrochloric Acid SCHEMBL30767142 0.77 LMNA (0.37) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL10360843 0.74 EHMT2 (0.43) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL27094915 0.74 HPGD (0.34) CYP2C9CYP2C19ALDH1A1LMNASMN1; SMN2
SCHEMBL3469006 0.74 EHMT2 (0.40) EHMT2EHMT1APOBEC3GALDH1A1LMNA
SCHEMBL28514925 0.74 LMNA (0.45) EHMT2EHMT1APOBEC3GALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2318838-B1 HIGH CAPACITY SOLID PHASE RADIOMETER MEDICAL APS (DK) 2013-09-04 EP claimed
CN-118873680-A Antibody-urease conjugates for therapeutic purposes 赫利克斯生物药品公司 2024-11-01 CN disclosed
CN-115175704-A Interleukin 10 conjugates and uses thereof 新索思股份有限公司 2022-10-11 CN disclosed
EP-3959319-A1 NUCLEIC ACID COMPOSITIONS AND METHODS OF MULTI-EXON SKIPPING Avidity Biosciences, Inc. (US) 2022-03-02 EP disclosed