SCHEMBL28514925

SCHEMBL28514925

CCC(=O)ON1C(=O)CCC1=O.c1ccc(SSc2ccccn2)nc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
EHMT2 Q96KQ7 1/20 0.44
EHMT1 Q9H9B1 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.38
ALDH1A1 P00352 6/20 0.37
RAB9A P51151 5/20 0.37
KMT2A Q03164 3/20 0.37
NPC1 O15118 2/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
POLB P06746 1/20 0.37
HSD17B10 Q99714 2/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALOX15 P16050 1/20 0.36
ATM Q13315 1/20 0.35
PKM P14618 1/20 0.35
ADORA3 P0DMS8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12092095 0.85 LMNA (0.42) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2
SCHEMBL19209537 0.83 APOBEC3G (0.40) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2
SCHEMBL11367709 0.83 LMNA (0.39) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2
SCHEMBL29352062 0.82 ALDH1A1 (0.44) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2
SCHEMBL42368 0.82 ALDH1A1 (0.44) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2
SCHEMBL321113 0.82 LMNA (0.38) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2
SCHEMBL29351145 0.82 LMNA (0.38) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2
SCHEMBL22414810 0.82 LMNA (0.38) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2
SCHEMBL29414992 0.82 LMNA (0.38) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2
SCHEMBL8610607 0.82 LMNA (0.38) LMNAEHMT2EHMT1APOBEC3GSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112175090-B Human lysozyme conjugate and preparation method and application thereof 深圳市雅臣智能生物工程有限公司 2024-04-26 CN disclosed
CN-117797255-A Composition, nano particles, external preparation and application for treating HPV infection 包晟 2024-04-02 CN disclosed
CN-108430514-B Compositions and methods for treating peroxisome disorders and leukodystrophies 约翰霍普金斯大学 2023-11-03 CN disclosed
CN-112175090-A Human lysozyme conjugate and preparation method and application thereof 深圳市雅臣智能生物工程有限公司 2021-01-05 CN disclosed