Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227783 | 0.76 | HSD17B10 (0.39) | EHMT2EHMT1APOBEC3GALDH1A1SMN1; SMN2 | |
| SCHEMBL1477669 | 0.76 | SLC22A12 (0.36) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL43721 | 0.75 | POLB (0.32) | POLB | |
| SCHEMBL15225100 | 0.74 | EHMT2 (0.35) | EHMT2EHMT1APOBEC3GALDH1A1SMN1; SMN2 | |
| SCHEMBL29414992 | 0.72 | LMNA (0.38) | EHMT2EHMT1APOBEC3GALDH1A1SMN1; SMN2 | |
| SCHEMBL22414810 | 0.72 | LMNA (0.38) | EHMT2EHMT1APOBEC3GALDH1A1SMN1; SMN2 | |
| SCHEMBL2002795 | 0.72 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2HSD17B10HPGDMAPT | |
| Hydrochloric Acid SCHEMBL30767154 | 0.72 | LMNA (0.38) | EHMT2EHMT1APOBEC3GALDH1A1SMN1; SMN2 | |
| SCHEMBL30952819 | 0.72 | LMNA (0.38) | EHMT2EHMT1APOBEC3GALDH1A1SMN1; SMN2 | |
| SCHEMBL25854342 | 0.72 | KDM4E (0.37) | EHMT2EHMT1APOBEC3GALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942996-B1 | THROMBOLYTIC AGENTS WITH ANTITHROMBOTIC ACTIVITY | DIATIDE INC (US) | 2007-01-03 | — | — | EP | claimed |
| CN-118490619-A | Immune activation microneedle and preparation method and application thereof | 山东大学齐鲁医院 | 2024-08-16 | — | — | CN | disclosed |
| US-20200046737-A1 | METHODS FOR TREATING CANCER, AND COMPOSITIONS THEREFOR | NOTABLE LABS INC (US) | 2020-02-13 | — | — | US | disclosed |
| WO-2020033851-A1 | COMPOSITIONS COMPRISING PRIMING AGENTS AND THEIR USE IN THE TREATMENT OF CANCER | Notable Labs, Inc. (US) | 2020-02-13 | — | — | WO | disclosed |
| US-9708410-B2 | Anti-tissue factor antibodies and compositions | JANSSEN BIOTECH, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20150175701-A1 | OVR110 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS, INC. (US) | 2015-06-25 | — | — | US | disclosed |
| EP-1819359-B1 | ANTI-INTEGRIN IMMUNOCONJUGATES, METHODS OF THEIR PRODUCTION AND THEIR USE | JANSSEN BIOTECH INC (US) | 2015-03-18 | — | — | EP | disclosed |
| US-8933050-B2 | Methods for the treatment and the diagnosis of cancer | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2015-01-13 | — | — | US | disclosed |
| US-8603483-B2 | Anti-integrin immunoconjugates, methods and uses | JANSSEN BIOTECH, INC. (US) | 2013-12-10 | — | — | US | disclosed |
| US-20130224776-A1 | PCan065 Antibody Compositions and Methods of Use | DIADEXUS, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| US-20050163832-A1 | Intracellular delivery of therapeutic agents | TORCHILIN VLADIMIR (US) | 2005-07-28 | — | — | US | disclosed |
| US-20030232968-A1 | Dendritic poly (amino acid) carriers and methods of use | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2003-12-18 | — | — | US | disclosed |
| EP-1315512-A2 | ADENOVIRAL TARGETING AND MANIPULATION OF IMMUNE SYSTEM RESPONSE USING TARGETING PEPTIDES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002020724-A2 | ADENOVIRAL TARGETING AND MANIPULATION OF IMMUNE SYSTEM RESPONSE USING TARGETING PEPTIDES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-03-14 | — | — | WO | disclosed |
| US-5459080-A | Ion-capture assays using a specific binding member conjugated to carboxymethylamylose | ABBOTT LABORATORIES (US) | 1995-10-17 | — | — | US | disclosed |
| US-5124441-A | Heterodisulfide derivatives of melphalan, penicillins, cephalosporins or anthracyclines releasing an active thiol derivative in vivo; bactericides; antitumor and -carcinogenic agents | PHARMACIA AKTIEBOLAG (SE) | 1992-06-23 | — | — | US | disclosed |
| EP-0060123-B1 | ASSAY AND USE | Self, Colin Henry (GB) | 1986-10-29 | — | — | EP | disclosed |
| EP-0064040-B1 | THERAPEUTICALLY ACTIVE DISULPHIDE COMPOUNDS AND THEIR USE | PHARMACIA AKTIEBOLAG (SE) | 1985-08-28 | — | — | EP | disclosed |
| EP-0064040-A1 | Therapeutically active disulphide compounds and their use | PHARMACIA AKTIEBOLAG (SE) | 1982-11-03 | — | — | EP | disclosed |
| EP-0060123-A1 | Assay and use | Self, Colin Henry (GB) | 1982-09-15 | — | — | EP | disclosed |