Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522529 | 0.88 | AKR1C3 (0.34) | ALDH1A1POLBAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1522647 | 0.77 | ALDH1A1 (0.53) | HSD17B10ALDH1A1MAPK1LMNACA12 | |
| SCHEMBL3390541 | 0.77 | ALDH1A1 (0.42) | HSD17B10ALDH1A1CXCR2POLBMAPK1 | |
| SCHEMBL1523638 | 0.74 | AKR1C3 (0.48) | ALDH1A1POLBAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1523741 | 0.74 | AKR1C3 (0.48) | POLBAKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL8286607 | 0.74 | CA12 (0.53) | HSD17B10ALDH1A1CXCR2POLBMAPK1 | |
| SCHEMBL1523409 | 0.69 | CA12 (0.40) | HSD17B10ALDH1A1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29889833 | 0.67 | POLB (0.53) | ALDH1A1POLBAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1999919 | 0.67 | POLB (0.53) | ALDH1A1POLBAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1522649 | 0.67 | ALDH1A1 (0.41) | HSD17B10ALDH1A1LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |