Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522527 | 0.88 | HSD17B10 (0.37) | AKR1C3AKR1C2AKR1C1PTGS1ALDH1A1 | |
| SCHEMBL1522649 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL1523640 | 0.74 | AKR1C3 (0.48) | AKR1C3AKR1C2AKR1C1PTGS1ALDH1A1 | |
| SCHEMBL1523744 | 0.74 | AKR1C3 (0.48) | AKR1C3AKR1C2AKR1C1PTGS1ALDH1A1 | |
| SCHEMBL1523582 | 0.69 | ALDH1A1 (0.32) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL1523412 | 0.69 | CA12 (0.37) | AKR1C3AKR1C2AKR1C1PTGS1ALDH1A1 | |
| SCHEMBL1999919 | 0.67 | POLB (0.53) | AKR1C3AKR1C2AKR1C1PTGS1ALDH1A1 | |
| SCHEMBL29889833 | 0.67 | POLB (0.53) | AKR1C3AKR1C2AKR1C1PTGS1ALDH1A1 | |
| SCHEMBL1522647 | 0.67 | ALDH1A1 (0.53) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL3390541 | 0.67 | ALDH1A1 (0.42) | ALDH1A1LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |