Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 7/20 | 0.50 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA9 | Q16790 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.50 |
| ▸ | CA6 | P23280 | 5/20 | 0.50 |
| ▸ | CA5A | P35218 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.50 |
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629218 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4ECYP3A4MEN1NPC1 | |
| SCHEMBL30908409 | 0.83 | CYP3A4 (0.50) | ALDH1A1KDM4ECYP3A4MEN1NPC1 | |
| SCHEMBL20150187 | 0.83 | CYP3A4 (0.50) | ALDH1A1KDM4ECYP3A4MEN1NPC1 | |
| SCHEMBL9326968 | 0.82 | KDM4E (0.58) | ALDH1A1KDM4ECYP3A4MEN1NPC1 | |
| SCHEMBL8776028 | 0.81 | CYP3A4 (0.48) | ALDH1A1KDM4ECYP3A4MEN1NPC1 | |
| SCHEMBL153905 | 0.81 | TDP1 (0.48) | ALDH1A1KDM4ECYP3A4MEN1NPC1 | |
| SCHEMBL29659353 | 0.81 | TDP1 (0.48) | ALDH1A1KDM4ECYP3A4MEN1NPC1 | |
| SCHEMBL13379613 | 0.81 | CYP3A4 (0.48) | ALDH1A1KDM4ECYP3A4MEN1NPC1 | |
| SCHEMBL1299062 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4ECYP3A4MEN1NPC1 | |
| Methylamine SCHEMBL7900082 | 0.79 | TDP1 (0.46) | ALDH1A1KDM4ECYP3A4MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3670490-B1 | METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES | KRATON POLYMERS LLC (US) | 2023-01-18 | — | — | EP | claimed |
| EP-3670490-A1 | METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES | Kraton Polymers LLC (US) | 2020-06-24 | — | — | EP | claimed |
| US-20200165191-A1 | Method of Purifying Pine Chemical Compositions from Aldehydes | KRATON POLYMERS LLC (US) | 2020-05-28 | — | — | US | claimed |
| EP-3670490-B1 | METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES | KRATON POLYMERS LLC (US) | 2023-01-18 | — | — | EP | disclosed |
| CN-115611897-A | Compounds as RSK2 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-01-17 | — | — | CN | disclosed |
| US-10822302-B2 | Method of purifying pine chemical compositions from aldehydes | KRATON POLYMERS LLC (US) | 2020-11-03 | — | — | US | disclosed |
| EP-3670490-A1 | METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES | Kraton Polymers LLC (US) | 2020-06-24 | — | — | EP | disclosed |
| US-20200165191-A1 | Method of Purifying Pine Chemical Compositions from Aldehydes | KRATON POLYMERS LLC (US) | 2020-05-28 | — | — | US | disclosed |
| EP-2038286-B1 | PYRRO[1,2-B]PYRIDAZINONE COMPOUNDS | ANADYS PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9145380-B2 | Bis-(sulfonylamino) derivatives for use in therapy | ASTRAZENECA AB (SE) | 2015-09-29 | — | — | US | disclosed |
| US-8404036-B2 | Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-26 | — | — | US | disclosed |
| WO-2002098424-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-12-12 | — | — | WO | disclosed |
| EP-1233953-A1 | NOVEL BENZOTHIADIAZINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2002-08-28 | — | — | EP | disclosed |
| CN-1081633-C | 1,2, 4-benzothiadiazine derivatives, method for preparing same and use thereof | NOVO NORDISK AS (DK) | 2002-03-27 | — | — | CN | disclosed |
| WO-2001040210-A1 | NOVEL BENZOTHIADIAZINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2001-06-07 | — | — | WO | disclosed |
| US-6242443-B1 | 1,2,4-benzothiadiazine derivatives, their preparation and use | NOVO NORDISK AIS (DK) | 2001-06-05 | — | — | US | disclosed |
| CN-1222910-A | 1,2, 4-benzothiadiazine derivatives, method for preparing same and use thereof | NOVO NORDISK AS (DK) | 1999-07-14 | — | — | CN | disclosed |
| EP-0906297-A1 | 1,2,4-BENZOTHIADIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997049692-A1 | 1,2,4-BENZOTHIADIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-12-31 | — | — | WO | disclosed |
| WO-1993021171-A1 | USE OF 2H-1,2,4-BENZOTHIADIAZINE-1,1-DIOXIDE-3-CARBOXYLIC ACID DERIVATIVES FOR PREPARING NMDA/AMPA RECEPTOR ANTAGONIST DRUGS, NOVEL PRODUCTS, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1993-10-28 | — | — | WO | disclosed |