Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150187 | 1.00 | CYP3A4 (0.50) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL1522533 | 0.83 | ALDH1A1 (0.59) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL23084394 | 0.82 | CYP3A4 (0.54) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL153905 | 0.81 | TDP1 (0.48) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL13379613 | 0.81 | CYP3A4 (0.48) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL8776028 | 0.81 | CYP3A4 (0.48) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL29659353 | 0.81 | TDP1 (0.48) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL9175606 | 0.80 | L3MBTL1 (0.61) | CYP3A4TDP1ALOX15THRBL3MBTL1 | |
| SCHEMBL7185812 | 0.79 | L3MBTL1 (0.48) | SMN1; SMN2L3MBTL1ALDH1A1KDM4ECA1 | |
| SCHEMBL3844195 | 0.79 | TDP1 (0.46) | CYP3A4TDP1ALOX15TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |