SCHEMBL8776028

SCHEMBL8776028

Cc1ccc(N)c(S(=O)(=O)Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
ALOX15 P16050 2/20 0.48
TP53 P04637 1/20 0.48
THRB P10828 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 2/20 0.42
TSHR P16473 1/20 0.41
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MAPT P10636 2/20 0.39
ATM Q13315 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
APP P05067 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA1 P00915 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1522533 0.81 ALDH1A1 (0.59) CYP3A4TDP1ALOX15TP53THRB
SCHEMBL20150187 0.81 CYP3A4 (0.50) CYP3A4TDP1ALOX15TP53THRB
SCHEMBL30908409 0.81 CYP3A4 (0.50) CYP3A4TDP1ALOX15TP53THRB
SCHEMBL2426442 0.80 TRPV4 (0.42) SMN1; SMN2ALDH1A1KDM4ETSHRMAPT
SCHEMBL29627448 0.80 TRPV4 (0.42) SMN1; SMN2ALDH1A1KDM4ETSHRMAPT
SCHEMBL27288311 0.80 ALDH1A1 (0.44) CYP3A4TDP1ALOX15TP53THRB
SCHEMBL29659353 0.79 TDP1 (0.48) CYP3A4TDP1ALOX15TP53THRB
SCHEMBL153905 0.79 TDP1 (0.48) CYP3A4TDP1ALOX15TP53THRB
SCHEMBL13379613 0.79 CYP3A4 (0.48) CYP3A4TDP1ALOX15TP53THRB
SCHEMBL742725 0.78 KMT2A (0.49) TDP1SMN1; SMN2ALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693461-A GELATIN-GRAFTED-POLYMER PARTICLES AND SILVER HALIDE GELATIN-PARTICLES; HETEROFLOCCULATED EMULSION; AT LEAST ONE OF THE PEPTIZING AND GRAFTED GELATINS IS AN ISOING GELATIN EASTMAN KODAK COMPANY (US) 1997-12-02 US disclosed
EP-0547912-B1 Silver halide photographic emulsion and light-sensitive silver halide color photographic material KONISHIROKU PHOTO IND (JP) 1997-11-19 EP disclosed
US-5486451-A FORMING A DISPERSION OF SILVER HALIDE GRAINS IN THE PRESENCE OF A HYDROPHILIC COLLOID AND REMOVING BY-PRODUCTS BY LOWERING THE PH TO BRING ABOUT COAGULATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-23 US disclosed
US-5478716-A Silver halide photographic emulsion containing silver iodobromide grains having two or more twin planes and light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1995-12-26 US disclosed
EP-0645672-A1 Method for preparing silver halide photographic emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-29 EP disclosed
EP-0547912-A1 Silver halide photographic emulsion and light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1993-06-23 EP disclosed
EP-0112162-B2 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1992-08-19 EP disclosed
EP-0165576-B1 PROCESS FOR PRODUCING SILVER BROMIDE OR IODOBROMIDE PHOTOGRAPHIC EMULSION KONICA CORPORATION (JP) 1992-01-02 EP disclosed
US-4942121-A PHOTOSTABILITY, QUALITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1990-07-17 US disclosed
EP-0176325-B1 LIGHT SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1990-04-04 EP disclosed
EP-0174873-A2 Silver halide color photo-sensitive material KONICA CORPORATION (JP) 1986-03-19 EP disclosed
US-4565778-A COMPRISING CORE/SHELL GRAINS OF SILVER IODOBROMIDE REPENED BY A LABILE SELENIUM COMPOUND;PHOTOSENSITIVITY;ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-01-21 US disclosed
EP-0165576-A2 Process for producing silver bromide or iodobromide photographic emulsion KONICA CORPORATION (JP) 1985-12-27 EP disclosed
EP-0145460-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1985-06-19 EP disclosed
EP-0121435-A1 Silver halide photographic materials KONICA CORPORATION (JP) 1984-10-10 EP disclosed
EP-0112162-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1984-06-27 EP disclosed
EP-0112161-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1984-06-27 EP disclosed
US-4442194-A Preparation of encapsulated electrostatographic toner material using gelatin derivative FUJI PHOTO FILM CO., LTD. (JP) 1984-04-10 US disclosed
US-4275145-A ANIONIC SURFACTANT, LECITHIN AND GELATIN DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1981-06-23 US disclosed
US-4200465-A Antistatic light-sensitive silver halide photographic element KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-04-29 US disclosed