Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MYLK | Q15746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15225787 | 0.76 | — | — | |
| SCHEMBL15225299 | 0.76 | — | — | |
| SCHEMBL15225872 | 0.76 | PRKCE (0.33) | MEN1ALDH1A1PRKCGMAPTPRKCA | |
| SCHEMBL15225694 | 0.74 | TSHR (0.32) | MEN1MAPTRECQLKMT2A | |
| SCHEMBL27875143 | 0.68 | MEN1 (0.37) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2862068 | 0.67 | LMNA (0.48) | MEN1ALDH1A1MAPTRECQLKMT2A | |
| SCHEMBL6941560 | 0.66 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL22991754 | 0.66 | TYR (0.65) | MEN1MAPTKMT2ATDP1 | |
| SCHEMBL2772333 | 0.65 | TAAR1 (0.54) | — | |
| SCHEMBL198567 | 0.64 | TSHR (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642880-B1 | HSP90 FAMILY PROTEIN INHIBITORS | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-09-04 | — | — | EP | claimed |