Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769748 | 0.88 | KCNH2 (0.36) | TSHRMAPK1CA2KCNH2ALDH1A1 | |
| SCHEMBL28096670 | 0.86 | KCNA3 (0.34) | TSHRMAPK1KCNH2ALDH1A1 | |
| SCHEMBL27773348 | 0.85 | TSHR (0.30) | TSHR | |
| SCHEMBL1627421 | 0.80 | SMN1; SMN2 (0.33) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL216358 | 0.79 | — | — | |
| SCHEMBL9474043 | 0.79 | — | — | |
| SCHEMBL9630323 | 0.79 | — | — | |
| SCHEMBL10710122 | 0.79 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL1985558 | 0.79 | TSHR (0.34) | TSHRCA2 | |
| SCHEMBL232619 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897644-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-10-27 | — | — | EP | claimed |
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | claimed |
| WO-2020132597-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2020-06-25 | — | — | WO | claimed |
| US-20200197391-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. | 2020-06-25 | — | — | US | claimed |
| US-7858802-B2 | Method of preparing ionic liquids | BASF SE (DE) | 2010-12-28 | — | — | US | claimed |
| EP-1246828-B1 | BENZOSULFONES WITH CALCIUM ANTAGONIST ACTIVITY | ORTHO MCNEIL PHARM INC (US) | 2005-12-07 | — | — | EP | claimed |
| US-20050084204-A1 | Digital dyes based on electrochemical redox reactions | HEWLETT-PACKARD DEVELOPMENT COMPANY L.P. | 2005-04-21 | — | — | US | claimed |
| EP-1192163-B1 | DITHIEPINO 6,5-b]PYRIDINES, AND RELATED COMPOSITIONS AND METHODS | ORTHO MCNEIL PHARM INC (US) | 2003-09-17 | — | — | EP | claimed |
| EP-0101023-A1 | Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-02-22 | — | — | EP | claimed |
| WO-2024149635-A1 | BRANCHED AMINES AS ADDITIVES FOR GASOLINE FUELS | BASF SE (DE) | 2024-07-18 | — | — | WO | disclosed |
| US-20240240095-A1 | NEW COMPOSITIONS FOR REDUCING CRYSTALLIZATION OF PARAFFIN CRYSTALS IN FUELS | BASF SE (DE) | 2024-07-18 | — | — | US | disclosed |
| US-20240217923-A1 | A DIISOCYANATE STABILIZER, USE THEREOF, AND DIISOCYANATE COMPOSITION | BASF (CHINA) COMPANY LIMITED (CN) | 2024-07-04 | — | — | US | disclosed |
| CN-118251435-A | Preparation and use of polyisocyanates containing iminooxadiazinedione groups | 巴斯夫欧洲公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115175967-B | Ionic liquids for stabilizing viscosity of silicate-based coatings | 巴斯夫欧洲公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-1980001690-A1 | CARBONYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS | EXXON RESEARCH ENGINEERING CO (US) | 1980-08-21 | — | — | WO | disclosed |
| WO-1980001692-A1 | TETRAALKYL PHOSPHONIUM SUBSTITUTED TRANSITION METAL COMPLEXES | EXXON RESEARCH ENGINEERING CO (US) | 1980-08-21 | — | — | WO | disclosed |
| US-4198205-A | SULFONIC ACID-FREE DISPERSE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4139537-A | 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds | COOPER LABORATORIES, INC. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200197391-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | KRAS, NRAS, HRAS | TSHR 2880/4885MAPK1 1658/4885CA2 4287/4885 |
| US-20240217923-A1 | A DIISOCYANATE STABILIZER, USE THEREOF, AND DIISOCYANATE COMPOSITION | TST, DDT, PAH | TSHR 2772/4885MAPK1 3568/4885CA2 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.