Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.73 |
| ▸ | PGR | P06401 | 5/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | DRD2 | P14416 | 1/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.70 |
| ▸ | USP2 | O75604 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | MLNR | O43193 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15225881 | 1.00 | NR3C1 (0.73) | NR3C1PGRNR1I2MAPTADORA3 | |
| SCHEMBL15225917 | 0.88 | NR3C1 (0.69) | NR3C1PGRNR1I2MAPTADORA3 | |
| SCHEMBL11420824 | 0.88 | NR3C1 (0.80) | NR3C1PGRNR1I2MAPTADORA3 | |
| SCHEMBL4215320 | 0.88 | PGR (0.70) | NR3C1PGRNR1I2MAPTADORA3 | |
| SCHEMBL11416504 | 0.87 | NR3C1 (0.83) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL9768468 | 0.85 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Dexamethasone Dipropionate SCHEMBL43107 | 0.85 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL10013893 | 0.85 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL20097870 | 0.85 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 | |
| Betamethasone Dipropionate SCHEMBL11429865 | 0.85 | NR3C1 (1.00) | NR3C1PGRNR1I2MAPTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004667-B1 | NOVEL 11 BETA - HYDROXYANDROSTA-4-ENE-3-ONES | SUN PHARMA ADVANCED RES CO LTD (IN) | 2013-09-04 | — | — | EP | disclosed |