SCHEMBL1522592

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1522591	0.92	MAPT (0.47)	MAPK1HSD17B10MAPTTHRBPTGDR2
	SCHEMBL1522525	0.91	MAPK1 (0.52)	MAPK1HSD17B10MAPTTHRBNR1I2
	SCHEMBL1522193	0.91	MAPK1 (0.57)	MAPK1HSD17B10MAPTTHRBPTGDR2
	SCHEMBL1522473	0.90	MAPK1 (0.58)	MAPK1HSD17B10MAPTPTGDR2NR1I2
	SCHEMBL1523104	0.90	MAPT (0.47)	MAPK1HSD17B10MAPTTHRBPTGDR2
	SCHEMBL1522295	0.89	MAPK1 (0.52)	MAPK1HSD17B10MAPTNR1I2CYP2C9
	SCHEMBL1523088	0.89	MAPK1 (0.54)	MAPK1HSD17B10THRBNR1I2CYP2C9
	SCHEMBL1522329	0.89	MAPK1 (0.54)	MAPK1HSD17B10PTGDR2NR1I2CYP2C9
	SCHEMBL1522694	0.89	MAPK1 (0.56)	MAPK1HSD17B10PTGDR2NR1I2CYP2C9
	SCHEMBL1523521	0.88	MAPK1 (0.56)	MAPK1HSD17B10THRBPTGDR2NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.