Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.45 |
| ▸ | FYN | P06241 | 7/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15226095 | 0.87 | ERN1 (0.46) | ERN1FYNRELAALDH1A1CYP3A4 | |
| SCHEMBL15225924 | 0.85 | TUBB1 (0.46) | ERN1FYNRELAALDH1A1CYP3A4 | |
| SCHEMBL15226008 | 0.83 | IMPDH2 (0.43) | FYNRELA | |
| SCHEMBL15225783 | 0.82 | ERN1 (0.49) | ERN1RELAALDH1A1CYP3A4TSHR | |
| SCHEMBL15225913 | 0.79 | ERN1 (0.50) | ERN1FYNRELAALDH1A1HSD17B10 | |
| SCHEMBL4038676 | 0.79 | ALDH1A1 (0.48) | RELAALDH1A1HSD17B10TUBB4ATUBB | |
| SCHEMBL4034103 | 0.78 | SMPD3 (0.40) | ERN1FYNRELATSHRTUBB4A | |
| SCHEMBL4038023 | 0.78 | HDAC8 (0.38) | ERN1FYNRELA | |
| SCHEMBL4034204 | 0.78 | TUBB4A (0.38) | ERN1FYNRELATUBB4ATUBB | |
| SCHEMBL15225910 | 0.78 | ERN1 (0.49) | ERN1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |