Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15226049 | 0.77 | KDM4E (0.48) | LMNAHTTKDM4ESIGMAR1CHRM5 | |
| SCHEMBL3660031 | 0.75 | CA1 (0.33) | — | |
| SCHEMBL5678515 | 0.74 | — | — | |
| SCHEMBL3958464 | 0.73 | CA1 (0.34) | KDM4E | |
| SCHEMBL3253967 | 0.73 | CA1 (0.32) | — | |
| SCHEMBL5189965 | 0.72 | POLB (0.46) | HTTKDM4ESIGMAR1CHRM5CHRM3 | |
| SCHEMBL15225779 | 0.72 | POLB (0.47) | HTTKDM4ESIGMAR1CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL17560392 | 0.71 | KDM4E (0.39) | HTTKDM4ESIGMAR1CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL17560389 | 0.71 | KDM4E (0.39) | HTTKDM4ESIGMAR1CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL5489333 | 0.70 | CHRNB2 (0.37) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | claimed |