Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660031 | 0.84 | CA1 (0.33) | CA1CA2CA4CA9 | |
| SCHEMBL20236395 | 0.83 | CA1 (0.35) | CA1CA2CA4CA9 | |
| SCHEMBL3253967 | 0.83 | CA1 (0.32) | CA1CA2CA4CA9 | |
| SCHEMBL28071026 | 0.80 | KDM4E (0.40) | KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL5489333 | 0.79 | CHRNB2 (0.37) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL34472707 | 0.76 | TP53 (0.32) | — | |
| SCHEMBL954795 | 0.74 | DPP4 (0.42) | CA1CA2CA4CA9KDM4E | |
| SCHEMBL954895 | 0.74 | DPP4 (0.42) | CA1CA2CA4CA9KDM4E | |
| SCHEMBL11361171 | 0.74 | APLNR (0.31) | APLNR | |
| SCHEMBL3958698 | 0.74 | CA1 (0.45) | CA1CA2CA4CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079756-A2 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF | Cara Therapeutics, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008060552-A2 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF | CARA THERAPEUTICS, INC. (US) | 2008-05-22 | — | — | WO | disclosed |