Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15225718 | 0.83 | TSHR (0.58) | POLBTSHRALDH1A1NPSR1HTT | |
| SCHEMBL15226049 | 0.79 | KDM4E (0.48) | POLBTSHRALDH1A1NPSR1HTT | |
| SCHEMBL4532848 | 0.77 | FKBP1A (0.38) | TSHRALDH1A1FKBP1A | |
| SCHEMBL8025147 | 0.77 | FKBP1A (0.38) | ALDH1A1FKBP1A | |
| SCHEMBL5678810 | 0.77 | L3MBTL1 (0.35) | TSHRALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15225968 | 0.72 | LMNA (0.48) | POLBALDH1A1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL6541621 | 0.72 | PARP1 (0.43) | TSHRALDH1A1NPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL7054243 | 0.72 | PARP1 (0.43) | TSHRALDH1A1NPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL7056396 | 0.72 | PARP1 (0.43) | TSHRALDH1A1NPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL3316200 | 0.71 | MAPT (0.39) | TSHRALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | claimed |